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The CRISPR-Cas9 system is widely used in gene editing, including gene knock-in, gene knock-out, gene activation, gene silencing, epigenetic modification, and 3D gene structure changes. sgRNA serves as a guide to recognize and combine a target with DNA, allowing activated Cas9 nuclease to attach, cleave, and modify the PAM downstream target DNA. sgRNAs are the key to the success of CRISPR gene editing experiments, such as how to reduce and avoid off-target effects and the accurate selection of sgRNA targets. Synbio Technologies provides efficient, accurate targeting, highly specific sgRNAs to researchers around the world. As a world-class sgRNA library designer and manufacturer, Synbio Technologies will lead the new revolution of gene editing.
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Relying on the world's leading sgRNA design platform and experienced professional team, Synbio Technologies provides animal, plant, and microbial sgRNA design and sgRNA vector construction services, including single sequence, specific pathway, whole-genome sgRNA design and ready-to-use sgRNA synthesis. We combined bioinformatics data with high-throughput screening validation to build an sgRNA data model with high editing efficiency. Accurate sgRNA design combined with precise synthesis can provide a reliable, validated, and efficient sequence of sgRNAs. Moreover, Synbio Technologies provides professional sgRNA bioinformatics services, and finally realizes an integrated service from sgRNA design, sgRNA library synthesis, and bioinformatics analysis.
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